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- Title
Needle-compatible single fiber bundle image guide reflectance endoscope.
- Authors
Jiantang Sun; Chenghao Shu; Benjamin Appiah; Rebekah Drezek
- Abstract
We developed a miniaturized high-resolution low-cost reflectance-mode fiber microscope (RFM) aimed at optical tissue biopsy applications using a polarized imaging configuration to suppress background noise from specular reflectance. The RFM is equipped with an air-cooled light-emitting-diode illumination module and a single 450-mouter-diameter fiber bundle image guide compatible with a 20-gaugeneedle. The dual illumination and image acquisition nature of the fiber bundle simplifies the system and reduces the total cost. Imaging tests with a United States Air Force resolution target demonstrate a lateral resolution of ∼3.5 m. The performance of the imaging system is evaluated by examining samples of cells and excised human tissue. Still and video rate images are obtainable in reflectance mode using intrinsic contrast.
- Subjects
FIBER bundles (Mathematics); ENDOSCOPES; NEEDLE biopsy; MEDICAL imaging systems; SPECULAR reflectance; TISSUE analysis; LIGHT emitting diodes
- Publication
Journal of Biomedical Optics, 2010, Vol 15, Issue 4, p040502
- ISSN
1083-3668
- Publication type
Article
- DOI
10.1117/1.3465558