We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Ureteral Stenting in Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy as a Routine Procedure: Evidence and Necessity.
- Authors
Coccolini, Federico; Lotti, Marco; Manfredi, Roberto; Catena, Fausto; Vallicelli, Carlo; De Iaco, Pier Andrea; Da Pozzo, Luigi; Frigerio, Luigi; Ansaloni, Luca
- Abstract
Introduction: There is a need for more exhaustive data concerning the use of prophylactic ureteral stenting for extended debulking and cytoreductive procedures in the literature. Material and Methods: A retrospective analysis of the CARPEPACEM study protocol database was performed. The trial protocol schedules the positioning of bilateral ureteral stents before cytoreductive surgery + hyperthermic intraperitoneal chemotherapy (HIPEC). Results: Fifty-one operated patients: 31 (59.6%) with peritoneal dissemination from ovarian cancer, 8 (15.3%) from colorectal cancer, 4 (7.9%) from pseudomyxoma peritonei, 3 (5.7%) from gastric cancer, 2 (3.8%) from peritoneal mesothelioma, 1 (1.9%) from appendiceal cancer, 1 (1.9%) from endometrial cancer, and 1 (1.9%) from leiomyosarcoma. Mean and median peritoneal cancer index: 11 and 10 (range: 0-28). CC-score: CC-0 in 45 (86.5%) patients, CC-1 in 5 (9.6%) and CC-2 in 1 (1.9%). HIPEC was performed with platinum + taxol in 22 patients (42.3%), platinum + adriablastin in 10 (19.2%), mitomycin in 9 (17.3%), platinum + mitomycin in 7 (13.4%), platinum + doxorubicin in 2 (3.8%), and taxol + adriablastin in 1 (1.9%). Two major ureteral complications were observed (3.9%). Discussion: Prophylactic ureteral stenting could reduce the risk of postoperative ureteral complications without an increase in stent placement-related complications; however, a randomized clinical trial is needed. Copyright © 2012 S. Karger AG, Basel
- Subjects
SURGICAL stents; URETER surgery; MALIGNANT hyperthermia; CANCER chemotherapy; TRANSURETHRAL prostatectomy; OPERATIVE surgery; DATA analysis
- Publication
Urologia Internationalis, 2012, Vol 89, Issue 3, p307
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000339920