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- Title
Mortality rate and its determinants among colorectal cancer patients in comprehensive specialized hospitals, Ethiopia: a retrospective cohort study.
- Authors
Atinafu, Bantalem Tilaye; Kebede, Worku Misganaw; Demlew, Tefera Mulugeta; Aynalem, Yared Asmare; Shiferaw, Wondimeneh Shibabaw; Tarekegn, Fetene Nigussie; Mulu, Getaneh Baye
- Abstract
Introduction: the mortality rate of colorectal cancer rises rapidly in low- and middle-income countries. Thus, this study aimed to assess the incidence of mortality and its determinant factors among colorectal cancer patients in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods: a retrospective cohort study was done among confirmed diagnoses of patients registered in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, between January 1st, 2013 to January 31st, 2016, followed up to January 31st, 2018. A total of 434 study participants were selected using census sampling. We performed training and pretest before the data was collected from patient record reviews. Data was entered using epi-data 4.2 and analyzed by STATA 14. Basic descriptive statistics were done. Kaplan Meier failure curve was used to show mortality differences among covariates. Bivariate and multivariable cox proportional hazard regression was done to show the net effect of independent variables. Results: among 434 study subjects, the cumulative incidence of death of colorectal cancer patients over the six-year follow-up period was 151 (34.8%). The overall mortality rate for diagnosed colorectal cancer patients during 818 person-year observations was 18.3 per 100 (95% CI: 15.7-21.7) person-year follow-up. Age =60 years old, marital status, comorbidity, stage, and grade of tumor were found to be significant predictors of mortality among confirmed diagnoses of colorectal cancer. Conclusion: the incidence of mortality among colorectal cancer patients was high. It is essential to establish screening protocol and provide brief interventions, where appropriate.
- Subjects
ETHIOPIA; MORTALITY; COLORECTAL cancer; CANCER patient care; MIDDLE-income countries
- Publication
Pan African Medical Journal One Health, 2022, Vol 7, p1
- ISSN
2707-2800
- Publication type
Article
- DOI
10.11604/pamj-oh.2022.7.26.29412