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- Title
Mycobacteria and Lymphoreticular Tumours in Xenopus Iaevis, the South African Clawed Toad.
- Authors
Clothier, R.H.; Balls, M.
- Abstract
Bacteria isolated from Xenopus lymphoreticular tumour cells were cultured and identified as Mycobacterium marinum, a well-known opportunistic pathogen. Large doses of the cultured bacteria induced granulomata in Xenopus toadlets. Lymphoreticular tumours were not induced either by lethal or sub-lethal doses of M. marinum, or by cell-free preparations made from the bacteria or from bacterium-infected cell cultures. These results suggest that the presence of mycobacteria is a secondary result and not, as has been suggested by others, a primary cause of lymphoreticular tumour lesions in Xenopus. Copyright © 1973 S. Karger AG, Basel
- Publication
Oncology, 1973, Vol 28, Issue 5, p445
- ISSN
0030-2414
- Publication type
Article
- DOI
10.1159/000224847