We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Epidermal homeostasis: a balancing act of stem cells in the skin.
- Authors
Blanpain, Cédric; Fuchs, Elaine
- Abstract
The skin epidermis and its array of appendages undergo ongoing renewal by a process called homeostasis. Stem cells in the epidermis have a crucial role in maintaining tissue homeostasis by providing new cells to replace those that are constantly lost during tissue turnover or following injury. Different resident skin stem cell pools contribute to the maintenance and repair of the various epidermal tissues of the skin, including interfollicular epidermis, hair follicles and sebaceous glands. Interestingly, the basic mechanisms and signalling pathways that orchestrate epithelial morphogenesis in the skin are reused during adult life to regulate skin homeostasis.
- Subjects
EPIDERMIS; STEM cells; HOMEOSTASIS; HAIR follicles; SEBACEOUS glands; MORPHOGENESIS
- Publication
Nature Reviews Molecular Cell Biology, 2009, Vol 10, Issue 3, p207
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm2636