We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis of some new 4-iminothiazolidine-2-ones as possible antioxidants agents.
- Authors
Chaban, Taras; Ogurtsov, Volodymyr; Chaban, Ihor; Myrko, Iryna; Harkov, Stefan; Lelyukh, Maryan
- Abstract
Novel N3 substituted derivatives of 4-iminothiazolidine-2-one were synthesised under the reactions of [2+3]cyclocondensation, thionation and aminolysis. The functionalisation of 3-phenyl-4-imino-thiazolydine-2-one was carried out in its C5 position under condensation Knoevenagel and nitrosation reactions. The antioxidant activity of the synthesised compounds was evaluated in vitro by the method of their scavenging effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. When compared with existing antioxidants, some of our compounds were found to be more potent.
- Subjects
THIAZOLIDINEDIONES; CHEMICAL synthesis; ANTIOXIDANTS; SULFURATION; NITROSATION
- Publication
Pharmacia (0428-0296), 2019, Vol 66, Issue 1, p27
- ISSN
0428-0296
- Publication type
Article
- DOI
10.3897/pharmacia.66.e35131