We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Natural history of gastric adenomas in patients with familial adenomatosis coli/Gardner's syndrome.
- Authors
Iida, Mitsuo; Yao, Tsuneyoshi; Itoh, Hideaki; Watanabe, Hidenobu; Matsui, Toshiyuki; Iwashita, Akinori; Fujishima, Masatoshi; Iida, M; Yao, T; Itoh, H; Watanabe, H; Matsui, T; Iwashita, A; Fujishima, M
- Abstract
The natural history of gastric adenomas was studied in 26 patients with familial adenomatosis coli (FAC)/Gardner's syndrome. The patients were followed for an average of 6.8 years (1 year, 5 months to 15 years 4 months) and examined repeatedly using gastric radiography, endoscopy, and biopsy. Gastric adenomas were present in 13 (50%). During the follow-up period, there was a new appearance of gastric adenomas in six patients but no distinct change in number, size, and histologic features in the remaining seven patients. In a 51-year-old man, an antral adenoma that measured 13 mm in diameter and had an irregular central depression did not change in size or morphology during 4 years and 1 month, but malignant change was evident at the time of endoscopic biopsy. The findings indicate that in patients with this disease, gastric adenomas require careful repeated follow-up examinations using endoscopic biopsy and, if feasible, endoscopic removal is recommended.
- Publication
Cancer (0008543X), 1988, Vol 61, Issue 3, p605
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19880201)61:3<605::AID-CNCR2820610331>3.0.CO;2-L