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- Title
Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency.
- Authors
Hancock, Shelley; Froehlich, Curtis; Armijo-Garcia, Veronica; Meyer, Andrew D.
- Abstract
Introduction: Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry. Case Report: A two-year-old male with a chest circumference less than a third percentile for age was admitted with influenza pneumonia developing a peak oxygenation index of 103.5. The child survived to baseline pulmonary function after nine days of venous-arterial ECMO support. Discussion: The ELSO registry contained 27 individuals with a surrogate diagnosis of thoracic insufficiency (0.05%). There was no significant difference in survival to discharge for thoracic insufficiency patients (52%) compared to a previously healthy population supported with ECMO. Conclusion: ECMO is safe and may be effective in supporting individuals with thoracic insufficiency.
- Subjects
RESPIRATORY insufficiency treatment; SPINE abnormalities; RIB abnormalities; REACTIVE oxygen species; CHI-squared test; CYANOSIS; REPORTING of diseases; EXTRACORPOREAL membrane oxygenation; FEVER; FISHER exact test; GENETIC disorders; INFLUENZA; OXYGEN in the body; PNEUMONIA; RESPIRATORY insufficiency; STATISTICS; THORACIC vertebrae; DATA analysis; RETROSPECTIVE studies; DATA analysis software; DESCRIPTIVE statistics; DISEASE complications; CHILDREN; PROGNOSIS
- Publication
Perfusion, 2018, Vol 33, Issue 8, p696
- ISSN
0267-6591
- Publication type
Article
- DOI
10.1177/0267659118778173