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- Title
A Case of More Abundant and Dysplastic Adenomas in the Interposed Colon than in the Native Colon.
- Authors
Hye Jin Hwang; Kyung Ho Song; Young Hoon Youn; Ji Eun Kwon; Hoguen Kim; Jae Bock Chung; Yong Chan Lee
- Abstract
We report a 60-year-old woman with intramucosal adenocarcinoma arising in the interposed colon, 40 years after the esophageal reconstruction for lye induced esophageal stricture. Although synchronous adenomas were also found in the native colon where the graft was taken, the number of adenomas was greater in the interposed colon and more dysplastic, even progressed to adenocarcinoma, than that of the native colon. The microsatellite instability-testing performed in the intramucosal carcinoma from interposed colon showed absence of microsatellite instability. Changing of location and functional deman]d of colonic segment, and the exposure to different intraluminal contents might have facilitated the adenomacarcinoma transformation in the interposed colon.
- Subjects
CANCER diagnosis; COLON cancer; ADENOCARCINOMA; ADENOMA; TUMORS
- Publication
Yonsei Medical Journal, 2007, Vol 48, Issue 6, p1075
- ISSN
0513-5796
- Publication type
Article
- DOI
10.3349/ymj.2007.48.6.1075