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- Title
Yoğun Bakım Hastalarında Gelişen Akut Böbrek Hasarında İskemi Modifiye Albümin ve Myeloperoksidaz Düzeyleri ile Epikardiyal Yağ Dokusu Kalınlığı İlişkisi.
- Authors
ÇANAKÇI, Ebru; KARATAŞ, Ahmet; DERELİ, Seçkin; KAYA, Yasemin; BAYRAK, Tülin; COŞKUN, İlker; ALTINBAŞ, Ali; CEBECİ, Zübeyir
- Abstract
Objective: The association between epicardial adipose tissue thickness, which is a determinant of endothelial dysfunction, and acute kidney injury (AKI) has not been investigated. Our aim in this study was to investigate the association between epicardial adipose tissue thickness, IMA, MPO levels and acute kidney injury. Material and Method: Seventy four AKI and 74 non-AKI cases in our intensive care units were included in the study. Furthermore, age, BMI, creatinine, e-GFR, CRP levels and APACHE II scores of each case were recorded. Results: There was no significant relationship between hypovitaminosis D and epicardial adipose tissue thickness (p >0.05). As E-GFR values increased, epicardial adipose tissue values decreased, and when E-GFR increased by one unit, epicardial adipose tissue thickness values decreased by 0.027 unit (p <0.001). As albumin levels increased, epicardial adipose tissue thickness values decreased, and when albumin increased by one unit, epicardial adipose tissue thickness values decreased by 0.706 unit (p =0.010). As the E-GFR values increased, the IMA values decreased, and when the E-GFR increased by one unit, the epicardial adipose tissue thickness values decreased by 0.001 unit (p =0.040). Conclusion: Epicardial adipose tissue thickness, which is a determinant of endothelial dysfunction and atherosclerotic plaque formation, can be safely used as a simple non-invasive determinant in AKI follow-up. Similarly, it may be assumed that both IMA and MPO are reliable biomarkers in the follow-up of AKI. Measuring epicardial adipose tissue thickness in the follow-up of AKI cases will be a rational and practical approach.
- Subjects
ADIPOSE tissues; ACUTE kidney failure; INTENSIVE care units; ATHEROSCLEROTIC plaque; ENDOTHELIUM diseases
- Publication
Firat Tip Dergisi, 2022, Vol 27, Issue 4, p269
- ISSN
1300-9818
- Publication type
Article