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- Title
Induction of Apoptosis in Human Lung Carcinoma A549 Epithelial Cells with an Ethanol Extract of Tremella mesenterica.
- Authors
Nan-Yin Chen; Hsi-Huai Lai; Tai-Hao Hsu; Fang-Yi Lin; Jian-Zhi Chen; Hui-Chen Lo
- Abstract
The article presents a study which determined the effects of extracellular polysaccharides (EPS), intracellular polysaccharides (IPS), and ethanol extract (EE) of Tremella mesenterica on the induction of apoptosis into human lung carcinoma A549 epithelial cells. Results of the study found a disruption of mitochondrial transmembrane potential, the production of reactive oxygen species (ROS), and the activation of caspase-3 protein in EE-treated cells.
- Subjects
APOPTOSIS; LUNG cancer; CELL death; TREMELLA; EXTRACELLULAR enzymes; REACTIVE oxygen species; EPITHELIAL cells
- Publication
Bioscience, Biotechnology & Biochemistry, 2008, Vol 72, Issue 5, p1283
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1271/bbb.70773