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- Title
Ten Flavonoids of Hypericum przewalskii and Selective Cytotoxicity Against Six Human Tumor Cell Lines.
- Authors
Zhang, Y.; Zhang, X. Q.; Yu, M. J.; Ren, C. Y.; Yu, X. H.; Yan, W.; Tang, J.
- Abstract
This article, published in the Chemistry of Natural Compounds journal, explores the chemical composition of Hypericum przewalskii, a plant used in traditional medicine. The researchers extracted compounds from the plant and identified ten flavonoids, including a new compound. They then tested the cytotoxicity of these compounds on six human tumor cell lines. The article provides detailed information on the chemical structure and properties of each compound. The study found that certain flavonols exhibited the strongest cytotoxic activity, and that hydrophobic compounds with a flat structure were more effective than hydrophilic compounds with a stereostructure. The research was supported by the Natural Science Research Project of colleges and Universities in Anhui Province.
- Subjects
CYTOTOXINS; CELL lines; HYPERICUM; FLAVONOIDS; SILICA gel
- Publication
Chemistry of Natural Compounds, 2024, Vol 60, Issue 3, p500
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-024-04361-z