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- Title
Fine-Tuning the Degree of Negative Charge and Carboxylate Grafting Density of Polymer-Coated Magnetite Nanoparticle.
- Authors
Usana Mahanitipong; Patcharin Kanhakeaw; Metha Rutnakornpituk
- Abstract
The surface of magnetite nanoparticle (MNP) was modified with poly(acrylic acid)(PAA)- poly(ethylene glycol) methyl methacrylate (PEGMA) (co)polymer to obtain water dispersible MNP with pH sensitive surfaces via atom transfer radical polymerization (ATRP) of tert-butyl acrylate (t-BA), followed by the t-BA group deprotection. Molar compositions of the (co)polymer were systematically varied, namely 100:0, 75:25, 50:50 and 25:75 of P(t-BA)/PEGMA, respectively, such that the grafting density of carboxylate groups on the MNP surface after the deprotection can be fine-tuned. Transmission electron microscopy (TEM) indicated that the MNP were spherical (ca.5-12 nm in diameter) with some nanoclustering observed. The roles of PAA and PEGMA affecting the hydrodynamic size and zeta potential of the nanocomposites observed via photocorrelation spectroscopy (PCS) were discussed. The percentages of the polymeric composition in the nanocomposites in each step of the reaction were determined via thermogravimetric analysis (TGA) and their magnetic properties were studied via vibrating sample magnetometry (VSM). These novel nanocomposites with pH sensitive surface and magnetically guidable properties might be advantageous for further conjugations either by covalent or ionic bonding with bioentities.
- Subjects
MAGNETITE; NANOPARTICLES; POLYELECTROLYTES; IONIC bonds; TRANSMISSION electron microscopy
- Publication
Trends in Sciences, 2023, Vol 20, Issue 3, p1
- ISSN
2774-0226
- Publication type
Article
- DOI
10.48048/tis.2023.6384