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- Title
Medikamentöse Schmerztherapie bei Patienten mit Tumorerkrankungen.
- Authors
Mütherig, Anke; Scheffler, Gesine; Schuler, Ulrich S.
- Abstract
Pharmacological pain therapy in cancer patients is based on guideline recommendations, which, however, do not fully coincide in all aspects due to varying weighting of evidence. The present article discusses current issues including the decreasing significance of the World Health Organization (WHO) analgesic ladder, with its distinction between step 2 and 3 being increasingly questioned. Risks of nonopioid analgesics such as paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs), particularly in older populations, are discussed. Paracetamol may potentially reduce the effectiveness of immunotherapies. Aspects of administering analgesics via a feeding tube are considered. Recommendations for the treatment of episodic pain, transitioning between different opioids, and some relevant interactions are also discussed.
- Subjects
WORLD Health Organization; CONTINUING education units; NONSTEROIDAL anti-inflammatory agents; MORPHINE; CANCER patients; CANCER pain; PAIN management; OPIOID analgesics; DRUG interactions; ACETAMINOPHEN; CANNABINOIDS
- Publication
Die Urologie, 2024, Vol 63, Issue 5, p497
- ISSN
2731-7064
- Publication type
Article
- DOI
10.1007/s00120-024-02347-x