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- Title
VÝZNAM POROVNATEĽNOSTI PODMIENOK LABORATÓRNEHO STANOVENIA ÚDAJOV V OBLASTI EXPERIMENTÁLNEJ BIOMEDICÍNY: SLABÉ STRÁNKY A RIZIKÁ SYSTÉMU LABORATÓRNYCH VYŠETROVACÍCH METÓD.
- Authors
Vladimír, MELUŠ; Zdenka, KRAJČOVIČOVÁ; Katarína, KAŠLÍKOVÁ; Pavel, GRABCZAK
- Abstract
Background: Contemporary biomedicine uses a wide range of laboratory investigation methods, which are different not only in terms of methodology, but also in terms of device design. This variability can negatively affect the results of the laboratory determination and, consequently, the interpretation of the results. Aim: The goal of our study was to verify the degree of agreement between the results of two devices in optical density examination of samples at a defined wavelength. Material and methods: For evaluation, we used Bland-Altman graphs for the results of measurements of 96 samples on a microtiter plate for three wavelengths (405 nm, 450 nm and 492 nm) and microorganisms S. aureus and E. coli. Results: The results verified the absence of agreement between the two compared devices in the determination of individual samples. Based on the mentioned facts, we accepted the results of the analyzer with lower variance. Conclusion: The mentioned cases can be a common complication of experiments and studies; therefore, it is necessary to take them into account when designing the study.
- Publication
Zdravotnicke listy, 2023, Vol 11, Issue 4, p40
- ISSN
1339-3022
- Publication type
Article