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- Title
STUDIU STATISTIC COMPARATIV PRIVIND LEZIUNILE CUTANATE ŞI ORALE PREMALIGNE ÎN JUDEŢELE MOLDOVEI.
- Authors
Temelie-Olinici, Doiniţa; Cotrutz, Carmen Elena; Grecu, Vasile Bogdan; Onofrei, Pavel; Gheucă-Solovăstru, Laura
- Abstract
Worldwide, numerous epidemiological studies have indicated a significant increase in the incidence of skin and oral premalignant lesions preceding squamous cell carinomas, which are among the most frequent and aggressive types of neoplasms detected in the last three decades. Although specialists find such lesions relatively easy to diagnose, patient survival and quality of life are not significantly improved even with expensive invasive treatment involving excision. This study provides a statistical analysis regarding the prevalence of cutaneous squamous cell carcinoma in premalignant lesions characteristic of actinic keratosis, Bowen's disease and keratocanthoma, compared to the occurrence of the same type of carcinoma in oral lesions specific to leukoplakia, oral lichen planus and actinic cheilitis. The data comes from the Anatomical Pathology and Morgue Service at the „St. Spiridon” Emergency Clinical Hospital in Iaºi and was collected over a period of five years (2013-2018). The results indicate an increased incidence of squamous cell carcinoma in oral premalignant lesions compared to those affecting the skin, in which case de novo developments are predominant. The study thus points to the hightened risk of malignant transformation in precancerous and oral lesions, and it prompts us to draw attention to the importance of early diagnosis before the onset of clinical symptoms.
- Publication
Dermatovenerologia Journal, 2019, Vol 64, Issue 3, p143
- ISSN
1220-3734
- Publication type
Article