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- Title
Application of Electron and Fluorescence Bronchoscope in the Diagnosis of Early Lung Cancer and Precancerous Lesions.
- Authors
ZHOU Ju-lan; ZHENG Yuan-yuan; HAO Qing-lin
- Abstract
Objective To evaluate the value of electronic bronchoscopy and fluorescencebronchoscope in the diagnosis of early stage lung cancer and precancerous lesions. Methods In the study, 120 patients with lung cancer by bronchoscopy and biopsy were assigned to receive electronic bronchoscopy ( n = 52) or fluorescen telectronic bronchoscopy (n = 68) in the First Affiliated Hospital of Kunming Medical University from January 2013 to June 2014. Results (1) The white light and fluorescence detecting severe atypical hyperplasia and carcinoma in situ respectively were (4, 1) and (8, 5) cases and the detection rates were 8.6% and 20.96% (χ² = 2.3286, P=0.0333). (2) The white light pathology in 58 cases were 28 cases, negative in pathology in 30 cases, of which 18 true positive, true negative in 22 cases, WLB I 14, WLB II 3, WLB III 11; self fluorescence pathology in 62 cases were 39 cases, negative in pathology in 21 cases, of which 35 true positive, true negative in 13 cases, in which AFB I 10, AFB II 11, AFB III 18. The analysis of the sensitive rate of white light bronchoscopy was 64.2%, specificity was 73.3%; fluorescence bronchoscope were 89.7% and 61.9%, the difference was statistically significant: susceptibility χ² = 13.4924, P <0.01; specificity χ² =6.0319, P <0.01. Conclusions Electronic bronchoscopy has an important role in diagnosis of lung cancer. Fluorescent electronic bronchoscopy, compared with electronic bronchoscopy, provides a more accurate diagnosis rate in diagnosis of early lung cancer.
- Subjects
LUNG cancer diagnosis; LUNG disease diagnosis; CANCER diagnosis; PRECANCEROUS conditions; BRONCHOSCOPY
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2015, Vol 36, Issue 3, p149
- ISSN
2095-610X
- Publication type
Article