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- Title
The association between birth weight and visceral fat in middle-age adults.
- Authors
McNeely, Marguerite J.; Fujimoto, Wilfred Y.; Leonetti, Donna L.; Tsai, Elaine C.; Boyko, Edward J.
- Abstract
<bold>Objective: </bold>Low birth weight, a proxy for fetal underdevelopment, is associated with increased risk of developing type 2 diabetes during adulthood. Low birth weight is also associated with central obesity, but little is known about the association between birth weight and visceral adiposity. The purpose of this study is to test the hypothesis that lower birth weight is associated with increased amounts of visceral fat in middle-age adults.<bold>Research Methods and Procedures: </bold>This is an observational study of 91 adults (58 men and 33 women) 40+/-6 years of age (mean+/-standard deviation). Ethnicity was either Japanese American (79%) or non-Hispanic white (21%). Birth weight was obtained from State Departments of Health. Measurements included smoking status, BMI, and visceral (intra-abdominal) fat measured by computed tomography.<bold>Results: </bold>Visceral fat was not associated with birth weight after adjustment for age, sex, ethnicity, BMI, or smoking status (p=0.76). There was no evidence that the association between birth weight and visceral fat varied by age, sex, or ethnicity.<bold>Discussion: </bold>We found no evidence that low birth weight is associated with increased visceral fat in middle-age adults.
- Subjects
BIRTH weight; FAT; MIDDLE-aged persons; TYPE 2 diabetes risk factors; ADULTS; HUMAN body composition; ADIPOSE tissues; BODY composition; COMPARATIVE studies; COMPUTED tomography; RESEARCH methodology; MEDICAL cooperation; TYPE 2 diabetes; OBESITY; REGRESSION analysis; RESEARCH; RESEARCH funding; EVALUATION research; BODY mass index; RELATIVE medical risk; STATISTICAL models; DIAGNOSIS
- Publication
Obesity (19307381), 2007, Vol 15, Issue 4, p816
- ISSN
1930-7381
- Publication type
journal article
- DOI
10.1038/oby.2007.596