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- Title
Effects of nonprescription therapies on vestibular migraine: a questionnaire‐based observational study.
- Authors
Hannigan, Imelda P.; Rosengren, Sally M.; Di Tanna, Gian L.; Watson, Shaun R. D.; Welgampola, Miriam S.
- Abstract
Background: Vestibular migraine (VM) is a common cause of recurrent vertigo. Migraine headache preventative therapies are currently prescribed to control vertigo symptoms in VM. Clinical trials of nutraceuticals for migraine headache prevention have shown positive outcomes, but, to date, there have been no studies to assess their effectiveness in the management of VM. Aims: To report the effects of nonprescription therapy management on VM symptoms. Methods: We undertook a prospective, questionnaire‐based assessment of patients diagnosed with VM between November 2019 and August 2021 at two Sydney tertiary referral clinics. Patients were advised on optimising sleep, hydration, exercise and nutrition and instructed to use an over‐the‐counter combination product containing riboflavin 200 mg, magnesium 150 mg, coenzyme Q10 75 mg and feverfew 200 mcg. Symptom severity and frequency were assessed using the Dizziness Handicap Inventory (DHI), the Vertigo Symptom Score short‐form (VSS‐sf) and two visual analogue scales for severity (VAS‐s) and frequency (VAS‐f) before and 3 months after commencing treatment. Result: In 82 participants (78% female; mean age, 44 ± 14 years) we recorded a decrease in DHI (mean, 16.8 [95% confidence interval (CI), 12.8–20.9], VSS‐sf (9.3, 7.1–11.5), VAS‐s (3.0, 2.2–3.8) and VAS‐f (2.8, 2.1–3.4), equating to an improvement of 44.1%, 44.9%, 44.1% and 38.9% for each measure respectively. On the DHI and VSS‐sf, 41 (50%) and 44 (53.7%) patients showed improvement in their symptoms; 39 (47.6%) and 36 (43.9%) patients noted no change and two patients reported worsening. The supplement was well‐tolerated. Conclusions: The results provide preliminary evidence that VM symptom frequency and severity can be reduced by using nonprescription therapies.
- Subjects
AUSTRALIA; UBIQUINONES; VERTIGO; EXERCISE; MAGNESIUM; RESEARCH funding; SCIENTIFIC observation; VISUAL analog scale; QUESTIONNAIRES; TREATMENT effectiveness; DESCRIPTIVE statistics; VITAMIN B2; SEVERITY of illness index; LONGITUDINAL method; VESTIBULAR apparatus diseases; SLEEP; FEVERFEW; CONFIDENCE intervals; MIGRAINE; NONPRESCRIPTION drugs; DIETARY supplements; NUTRITION; DISEASE risk factors
- Publication
Internal Medicine Journal, 2024, Vol 54, Issue 6, p916
- ISSN
1444-0903
- Publication type
Article
- DOI
10.1111/imj.16314