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- Title
Red/green opponency in the rhesus macaque ERG spectral sensitivity is reduced by bicuculline.
- Authors
Mills, Stephen L.; Sperling, Harry G.
- Abstract
Spectral-sensitivity curves were derived from the a−, b−, and d−waves of rhesus monkey ERGs after injection of bicuculline, strychnine, or no drug. Without drug injection, the a− and d−wave curves were well-fit by an additive model of weighted photoreceptor absorption spectra, while the b−wave curve requires inhibitory terms to produce an adequate fit. Bicuculline, but not strychnine, reduced the weight assigned to the inhibitory terms in a dose-dependent fashion, to the point that no inhibition was evident. The results suggest that GABAergic synapses are required for the expression of red/green color opponency in primate bipolar cells.
- Publication
Visual Neuroscience, 1990, Vol 5, Issue 3, p217
- ISSN
0952-5238
- Publication type
Article
- DOI
10.1017/S0952523800000286