We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
NUP98–HMGB3: a novel oncogenic fusion.
- Authors
Petit, A; Ragu, C; Della-Valle, V; Mozziconacci, M J; Lafage-Pochitaloff, M; Soler, G; Schluth, C; Radford, I; Ottolenghi, C; Bernard, O A; Penard-Lacronique, V; Romana, S P
- Abstract
The article discusses about the NUP98 promiscuou gene. It is involved in chromosomal aberrations with other genes in variety of human hematological malignancies. Study of overexpression in mouse bone marrow indicates that NUP98 induce leukemic transformation. The article reports about the involvement of NUP98 in the therapy related acute myeloblastic leukemia. The article also describes the process of NUP98-HMBG3 fusion. Various charts related to the experiment is presented.
- Subjects
CANCER; BONE marrow; GENES; LEUKEMIA; CANCER genes; CHARTS, diagrams, etc.
- Publication
Leukemia (08876924), 2010, Vol 24, Issue 3, p654
- ISSN
0887-6924
- Publication type
Article
- DOI
10.1038/leu.2009.241