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- Title
Antibody response to Influenza booster vaccination in Franches‐Montagnes stallions supplemented with Equi‐Strath<sup>®</sup>: a randomized trial.
- Authors
van Dorland, Hendrika A.; Zanoni, Reto; Gerber, Vinzenz; Jeannerat, Elise; Wiederkehr, Danja; Burger, Dominik
- Abstract
Abstract: Bio‐Strath® is a plasmolyzed yeast product enriched with herbs, malt, honey and orange juice. In this study, the effect of Equi‐Strath®, the adapted product for horses, on the equine immune system was evaluated. A routine influenza booster vaccination was used as a model to study the effects of Equi‐Strath® supplementation on the immune response. Twenty healthy Franches‐Montagnes stallions with pre‐existing antibody levels were randomly divided into a study group (SG, n = 10) receiving 0.06 mL/kg bodyweight of Equi‐Strath®, and a control group (CG, n = 10), receiving the same amount of placebo, daily. The supplement and placebo were given from week 1 until week 14 of the trial. After 10 weeks, the horses were vaccinated with a commercial vaccine containing equine influenza strains of the H3N8 subtype. Antibody titres in blood were measured at day 0 before vaccination, and 14 and 32 days after vaccination. In addition, a complete blood count (CBC) was performed on day 0 and day 32. A linear increase of haemagglutination inhibition titres in both groups was observed after vaccination, but with no difference between treatment groups. CBC components remained unaffected by treatment. In conclusion, daily Equi‐Strath® supplementation did not affect the adaptive immune response in stallions after a routine commercial H3N8 influenza booster vaccination.
- Subjects
ANTIBODY formation; INFLUENZA vaccines; STALLIONS; BLOOD agglutination; VETERINARY immunology; RANDOMIZED controlled trials; DISEASES
- Publication
Veterinary Medicine & Science, 2018, Vol 4, Issue 2, p133
- ISSN
2053-1095
- Publication type
Article
- DOI
10.1002/vms3.95