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- Title
Exploration of Bioactive Compounds from Sargassum myriocystum; A Novel Approach on Catalytic Inhibition Against Free Radical Formation and Glucose Elevation.
- Authors
Vinodkumar, Maheswari; Packirisamy, Azhagu Saravana Babu
- Abstract
The importance of bioactive substances from seaweeds has grown as a result of their capacity to promote human disease resistance and enhance human health. Secondary metabolites from brown marine algae could serve as a good source of phytochemicals with rich anti-oxidant ability, as most of the ailments are associated with free radicals. This research is focused on looking into the brown algal species Sargassum myriocystum belonging to the class Phaeophyceae, which has not been investigated for the presence of different bioactive compounds. The efficient extraction of and the qualitative analysis of the phytochemical compounds were performed and characterized. Moreover, the characteristic functional and bioactive molecules in the extract at optimum conditions were evaluated which showed the presence of various bioactive compounds. The antioxidant and anti-inflammatory potential of the extract indicated the potential reduction of free radicals and inflammatory mediators by the seaweed extract. The inhibition of digestive enzymes including α-amylase and α-glucosidase exhibited promising anti-diabetic potential and the antimicrobial property against some gram negative, gram positive bacteria and fungus was evaluated which inhibited the growth of microbes. Hence, the present study may provide the platform for utilizing bioactive compounds from brown seaweed as a promising therapeutic agent from natural source.
- Subjects
GLYCOGENOLYSIS; BIOACTIVE compounds; FREE radicals; SARGASSUM; MARINE algae; GRAM-negative bacteria; DIGESTIVE enzymes; GLUCOSIDASES
- Publication
Topics in Catalysis, 2024, Vol 67, Issue 1-4, p60
- ISSN
1022-5528
- Publication type
Article
- DOI
10.1007/s11244-023-01831-6