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- Title
NECROTIZING ENTEROCOLITIS IN LOW WEIGHT NEWBORNS: HIERARCHIZED ANALYSIS OF ASSOCIATED FACTORS.
- Authors
Santana Costa Buna, Camila Maria; Oliveira Serra, Humberto; Moreira da Silva Soeiro, Vanessa; Lopes Ericeira, Vanessa Virgínia; de Jesus Mendes Caldas, Arlene
- Abstract
Objective: To analyze the occurrence of necrotizing enterocolitis and the factors associated with its development in infants of low birth weight. Methods: Case-control study, 1:3, 95% confidence level and 80% study power, total of 236 newborns with low weight, 59 infants with diagnosis of necrotizing enterocolitis and 177 RN without. Maternal and neonatal variables were organized into blocks and levels (distal, intermediate and proximal). To verify association with the response variable NEC, hierarchical logistic regression was used. Results: Statistically significant association with NEC, antenatal corticosteroid use (OR = 2.90; p <0.001), reduced amniotic fluid (OR = 2.03; p <0.001), resuscitation at birth (OR = 1), 35; p = 0.010), birth weight ≤1500g (OR = 3.32; p <0.001), transfusion (OR = 2.11; p = 0.040) and surfactant use (OR = 2.41; p = 0.020). Conclusion: Factors related to gestational period, birth and hospitalization may be influencing the onset of NEC. Intervention in these variables may decrease the chance of NEC.
- Subjects
BRAZIL; NEONATAL necrotizing enterocolitis; NEONATAL intensive care; PREMATURE infants; CONFIDENCE intervals; ADRENOCORTICAL hormones; CASE-control method; NEONATAL intensive care units; AMNIOTIC liquid; LOW birth weight; DESCRIPTIVE statistics; LOGISTIC regression analysis; ODDS ratio; PRENATAL care; RESUSCITATION; DISEASE risk factors
- Publication
Revista de Pesquisa: Cuidado é Fundamental, 2021, Vol 13, Issue 1, p588
- ISSN
1809-6107
- Publication type
Article
- DOI
10.9789/2175-5361.rpcfo.v13.9327