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- Title
Angiosarcoma of the tongue: report of a case with immunohistochemical findings.
- Authors
Tabata, Masashi; Sugihara, Kazumasa; Matsul, Ryutaro; Yonezawa, Suguru; Abeyama, Kazuhiro; Maruyama, Ikuro; Tabata, M; Sugihara, K; Matsui, R; Yonezawa, S; Abeyama, K; Maruyama, I
- Abstract
A case report of angiosarcoma of the tongue is presented. The specimen revealed single and clustered large, pleomorphic, and spindle-shaped cells with a markedly hemorrhagic background. Tumor cells showed expression of thrombomodulin and E-selectin, but no expression of Factor VIII-related antigen, Ulex europaeus agglutinin-1, vascular endothelial growth factor, and CD34. In the current study, immunohistochemical results using antibodies against thrombomodulin and E-selection supported the diagnosis of angiosarcoma.
- Subjects
ANGIOSARCOMA; IMMUNOHISTOCHEMISTRY; THROMBOMODULIN; GENE expression; IMMUNOGLOBULINS; SELECTINS; ANTIGEN analysis; PROTEIN analysis; CELL receptors; DISEASE complications; IMMUNOENZYME technique; SARCOMA; TONGUE tumors; TREATMENT effectiveness
- Publication
Journal of Oral Pathology & Medicine, 1999, Vol 28, Issue 2, p92
- ISSN
0904-2512
- Publication type
journal article
- DOI
10.1111/j.1600-0714.1999.tb02003.x