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- Title
The Effects of MBL1 Gene Polymorphism on Subclinical Mastitis in Holstein Cows.
- Authors
AKSEL, Esma Gamze; AKÇAY, Aytaç; ARSLAN, Korhan; SOHEL, Mahmodul Hasan; GÜNGÖR, Güven; AKYÜZ, Bilal
- Abstract
This study aims to investigate the effects of three single nucleotide (SNPs) polymorphisms of the MBL1 gene on subclinical mastitis for Holstein cows. For this study, a total of 151 Holstein cows were selected in their third lactation. The subclinical mastitis conditions were determined using the California Mastitis Test (CMT). Genotyping was carried out with the PCR-RFLP method. The results revealed that the wild-type allele frequencies were 0.72 (G allele), 0.40 (G allele), and 0.37 (T allele) for 1252 G>A, 2534 G>A, and 2569 T>C SNPs, respectively. Among the investigated SNPs, only the 1252 G>A SNP was not found in Hardy-Weinberg equilibrium. The effects of SNPs on subclinical mastitis were modeled using Multiple Logistic Regression Analysis. The established model can identify cows with subclinical mastitis with a separation efficiency of 62.3%. It was thought that 1252 G>A and 2534 G>A SNPs may affect subclinical mastitis rates.
- Subjects
MASTITIS; GENETIC polymorphisms; MULTIPLE regression analysis; COWS; LOGISTIC regression analysis; SINGLE nucleotide polymorphisms; GENE frequency
- Publication
Kafkas Universitesi Veteriner Fakultesi Dergisi, 2021, Vol 27, Issue 3, p389
- ISSN
1300-6045
- Publication type
Article
- DOI
10.9775/kvfd.2021.25714