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- Title
Correction to: 4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson's Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation.
- Authors
Tiwari, Shubhangini; Gupta, Parul; Singh, Abhishek; Chaturvedi, Swati; Wahajuddin, M.; Mishra, Amit; Singh, Sarika
- Abstract
SN Substantia nigra, STR Striatum, GFAP Glial Fibrillary Acidic Protein, C Sham-operated control, R Rotenone, PBA 4-Phenyl butyrate. 6 Protective effect of 4PBA on astrocyte activation after 3-days of rotenone treatment in SN and STR brain regions of SD rat. a and b Immunoblots and bar diagram indicate the protein level of GFAP showing the astrocytes activation in both SN [F(3,4) = 15.22; p = 0.0118] and STR [F(3,4) = 10.75; p = 0.0220] regions of rat brain with or without rotenone and 4PBA treatment, in comparison to loading control -action; n = 7 animals per group. c and d Fluorescent images and analysis (Image-J) based on the stereological cell count and % Area depict protective effect of 4PBA on the increased GFAP-positive immune-reactive astroglia cells in both SN and STR regions of the rat brain after 3-days of rotenone treatment, in comparison to the sham-operated control and 4PBA group, Scale bar- 50 µm; n = 7 animals per group.
- Subjects
PARKINSON'S disease; PATHOLOGY; GLIAL fibrillary acidic protein; FUNCTIONAL magnetic resonance imaging
- Publication
Neurochemical Research, 2023, Vol 48, Issue 10, p3251
- ISSN
0364-3190
- Publication type
Correction Notice
- DOI
10.1007/s11064-023-03975-z