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- Title
Structural and Functional Analyses of MRS (Major Repeated Sequnece) in Candida albicans.
- Authors
Chibana, Hiroji; Mikami, Yuzuru
- Abstract
There are several different types of repeated sequences in the genome of Candida albicans, including the MRS (Major repeated sequence). In 2004, the whole genome sequence of C. albicans was published. Assembly of the sequences to chromosomal length contigs was not achieved, mainly due to interruption of the sequences by MRS. However, MRS including Ca3, 27A and RPS have been playing important roles in a number of epidemiological research studies and basic biological investigations into C. albicans chromosome loss events and associated phenotypic changes. Here we summarize structural analyses from subrepeat sequences to the chromosome level, and functional analyses of MRS.
- Subjects
GENOMES; NUCLEOTIDE sequence; CANDIDA albicans; CHROMOSOMES; NUCLEIC acid analysis
- Publication
Japanese Journal of Medical Mycology, 2006, Vol 47, Issue 3, p129
- ISSN
0916-4804
- Publication type
Article
- DOI
10.3314/jjmm.47.129