We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Palladium‐Catalyzed Asymmetric Allylic Cycloaddition of Vinylethylene Carbonates with Nitroalkenes: A Route to Tetrahydrofurans bearing Vicinal Tetrasubstituted Stereocenters.
- Authors
Zhao, Can; Khan, Sardaraz; Khan, Ijaz; Shah, Babar Hussain; Zhang, Yong Jian
- Abstract
An efficient method for the diastereo‐ and enantioselective construction of tetrahydrofurans bearing three continuous stereocenters including vicinal tetrasubstituted stereocenters via palladium‐catalyzed asymmetric allylic cycloaddition of vinylethylene carbonates with nitroalkenes was developed. By using a palladium complex generated in situ from [Pd2(dba)3] ⋅ CHCl3 and (R)‐BINAP ligand as a catalyst under mild reaction conditions, the process provides multi‐functionalized tetrahydrofurans in good yields with excellent stereoselectivities.
- Subjects
RING formation (Chemistry); NITROALKENES; CARBONATES; PALLADIUM compounds; STEREOSELECTIVE reactions
- Publication
Asian Journal of Organic Chemistry, 2022, Vol 11, Issue 8, p1
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.202200313