Found: 33
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Wild Type and Tangier Disease ABCA1 Mutants Modulate Cellular Amyloid-β Production Independent of Cholesterol Efflux Activity.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 27, n. 2, p. 441, doi. 10.3233/JAD-2011-110521
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- Article
Investigation of Matrix Metalloproteinases, MMP-2 and MMP-9, in Plasma Reveals a Decrease of MMP-2 in Alzheimer's Disease.
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- Journal of Alzheimer's Disease, 2011, v. 26, n. 4, p. 779, doi. 10.3233/JAD-2011-101974
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- Article
Wild type and Tangier disease ABCA1 mutants modulate cellular amyloid-β production independent of cholesterol efflux activity.
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- 2011
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- Publication type:
- journal article
Investigation of matrix metalloproteinases, MMP-2 and MMP-9, in plasma reveals a decrease of MMP-2 in Alzheimer's disease.
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- 2011
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- Publication type:
- journal article
Critical analysis of the use of β-site amyloid precursor protein-cleaving enzyme 1 inhibitors in the treatment of Alzheimer's disease.
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- Degenerative Neurological & Neuromuscular Disease, 2014, v. 4, p. 1, doi. 10.2147/DNND.S41056
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- Article
A synthetic substrate assay for the gamma-secretase of the β-A4 amyloid of alzheimer's disease.
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- Journal of Peptide Science, 1995, v. 1, n. 2, p. 132, doi. 10.1002/psc.310010205
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- Article
Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Cu/Zn-Dependent Superoxide Dismutase Activtity
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- 2011
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- Abstract
Decreased expression of GGA1 and GGA3 adaptor proteins in Alzheimer's disease frontal cortex
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- 2009
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- Abstract
P4-206: Identification of gamma-secretase activities with distinct pharmacological properties
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- 2008
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- Abstract
P3-345: Presenilin-1 interacts with acetylcholinesterase
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- 2008
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- Abstract
P3-401: Characterization of gamma-secretase using a recombinant APP C99 substrate and compartive analysis of gamma-activity in mouse tissues
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- 2006
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- Abstract
P2-025: Copper depletion by menkes ATP7A over-expression dramatically alters the metabolism of APP and APLP2 in cell culture
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- 2006
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- Abstract
O3-03-06: Copper sensitively induces presenilin 1 lipid raft localization with increased amyloidogenic processing of the amyloid precursor protein
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- 2006
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- Abstract
P3-401: Characterization of gamma-secretase using a recombinant APP C99 substrate and compartive analysis of gamma-activity in mouse tissues
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- 2006
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- Publication type:
- Abstract
P2-025: Copper depletion by menkes ATP7A over-expression dramatically alters the metabolism of APP and APLP2 in cell culture
- Published in:
- 2006
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- Publication type:
- Abstract
O3-03-06: Copper sensitively induces presenilin 1 lipid raft localization with increased amyloidogenic processing of the amyloid precursor protein
- Published in:
- 2006
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- Publication type:
- Abstract
In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
- Published in:
- FEBS Journal, 2005, v. 272, n. 21, p. 5544, doi. 10.1111/j.1742-4658.2005.04950.x
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- Publication type:
- Article
Mild Oxidative Stress Induces Redistribution of BACE1 in Non-Apoptotic Conditions and Promotes the Amyloidogenic Processing of Alzheimer’s Disease Amyloid Precursor Protein.
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- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061246
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- Publication type:
- Article
Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
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- Journal of Neuroscience Research, 2003, v. 74, n. 3, p. 386, doi. 10.1002/jnr.10745
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- Publication type:
- Article
A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease.
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- Proteomics, 2010, v. 10, n. 12, p. 2377, doi. 10.1002/pmic.200900773
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- Article
Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies.
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- 2006
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- Publication type:
- journal article
Inhibition of γ-Secretase as a Therapeutic Intervention for Alzheimer’s Disease: Prospects, Limitations and Strategies.
- Published in:
- CNS Drugs, 2006, v. 20, n. 5, p. 351, doi. 10.2165/00023210-200620050-00002
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- Article
Increased β-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
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- Annals of Neurology, 2004, v. 55, n. 6, p. 898
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- Article
Increased expression of the amyloid precursor β-secretase in Alzheimer's disease.
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- Annals of Neurology, 2002, v. 51, n. 6, p. 783, doi. 10.1002/ana.10208
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- Article
β-Site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis.
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- Journal of Neurochemistry, 2012, v. 120, n. 6, p. 869, doi. 10.1111/j.1471-4159.2011.07623.x
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- Article
Products of the Alzheimer's disease amyloid precursor protein generated by,β-secretase are present in human platelets, and secreted upon degranulation.
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- American Journal of Alzheimer's Disease & Other Dementias, 1998, v. 13, n. 5, p. 236, doi. 10.1177/153331759801300504
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- Publication type:
- Article
Alzheimer's disease-associated presenilin 1 in neuronal cells: Evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.
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- Journal of Neuroscience Research, 1997, v. 49, n. 6, p. 719, doi. 10.1002/(SICI)1097-4547(19970915)49:6<719::AID-JNR6>3.0.CO;2-A
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- Article
BACE1 as a Therapeutic Target in Alzheimer's Disease: Rationale and Current Status.
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- Drugs & Aging, 2013, v. 30, n. 10, p. 755, doi. 10.1007/s40266-013-0099-3
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- Article
How accelerated Golgi trafficking may drive Alzheimer's disease.
- Published in:
- 2015
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- Publication type:
- Opinion
Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
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- Journal of Neurochemistry, 2004, v. 91, n. 1, p. 230, doi. 10.1111/j.1471-4159.2004.02718.x
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- Article
Future Therapeutics in Alzheimer's Disease: Development Status of BACE Inhibitors.
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- BioDrugs, 2016, v. 30, n. 3, p. 173, doi. 10.1007/s40259-016-0168-3
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- Publication type:
- Article
A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease.
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- Proteomics - Clinical Applications, 2010, v. 4, n. 10/11, p. 851, doi. 10.1002/prca.201090068
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- Article
p75NTR Regulates Aβ Deposition by Increasing Aβ Production But Inhibiting Aβ Aggregation with Its Extracellular Domain.
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- Journal of Neuroscience, 2011, v. 31, n. 6, p. 2292, doi. 10.1523/JNEUROSCI.2733-10.2011
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- Article