We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Gene-environment interaction in posttraumatic stress disorder: An update.
- Authors
Koenen, Karestan C.; Amstadter, Ananda B.; Nugent, Nicole R.
- Abstract
The authors provide a detailed review of the extant gene–environment interaction (GxE) research in the etiology of posttraumatic stress disorder (PTSD). They begin with a discussion of why PTSD is uniquely fitting for the innovative framework of GxE methodology, followed by a review of the heritability and main effect molecular genetics studies of PTSD. Next, they discuss the six GxE investigations to date on PTSD. They end with a discussion of future directions and significance of this research, with an emphasis on the expansion of psychosocial factors that may be fitting environmental variables for inclusion in this new research area. The authors posit that GxE research is vital to elucidating risk and resilience following exposure to a potentially traumatic event.
- Subjects
GENOTYPE-environment interaction; POST-traumatic stress disorder; ETIOLOGY of diseases; MOLECULAR genetics study &; teaching; PUBLIC health research; RESEARCH methodology; PSYCHOSOCIAL factors; POST-traumatic stress; PSYCHOSOMATIC disorders
- Publication
Journal of Traumatic Stress, 2009, Vol 22, Issue 5, p416
- ISSN
0894-9867
- Publication type
Article
- DOI
10.1002/jts.20435