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- Title
Qualitative and Quantitative Determination of the New Antiarrhythmic Drug Ritmidazole.
- Authors
Stepanov, A. V.; Smirnova, L. A.; Spasov, A. A.
- Abstract
Develops methods for the qualitative and quantitative determination of the antiarrhythmic drug ritmidazole by UV and fluorescence spectroscopies and HPLC. Use of a model-independent approach in the analysis; Regression analysis; Use of the Student t-criterion using an Excel 70 program package; Observation that the pharmacokinetic profile of ritmidazole in the whole blood virtually coincides with that in the blood plasma.
- Subjects
MYOCARDIAL depressants; CARDIOVASCULAR agents; ULTRAVIOLET spectroscopy; FLUORESCENCE spectroscopy; HIGH performance liquid chromatography; MATHEMATICAL statistics; REGRESSION analysis; PHARMACEUTICAL chemistry
- Publication
Pharmaceutical Chemistry Journal, 2003, Vol 37, Issue 8, p440
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1023/A:1027368316074