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- Title
Rapid electronic prediction of gene expression regulation in bacterial cells.
- Authors
Alam, S.; Lai, E. M-K.; Young, J.; Hasan, S. M. R.
- Abstract
A cytomorphic circuit that can mimic gene expression regulation mechanisms is presented. It is shown that this circuit can efficiently predict the cellular response of the bacterium Escherichia coli in real time. The simulation outputs of the circuit are compared with biological experimental results. The significant similarity between these results shows that the circuit can be used to predict cellular malfunctioning within microseconds.
- Subjects
BIOELECTRONICS; ELECTRONIC circuits; GENE expression; COMPUTER simulation; BACTERIAL cells; ESCHERICHIA coli
- Publication
Electronics Letters (Wiley-Blackwell), 2014, Vol 50, Issue 22, p1566
- ISSN
0013-5194
- Publication type
Article
- DOI
10.1049/el.2014.2144