We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Fisiopatologia dell'insufficienza cardiaca e principi di terapia.
- Authors
Toaldo, Marco Baron; Guglielmini, Carlo
- Abstract
The term heart failure (HF) identifies a syndrome, characterized by an inadequate organ perfusion secondary to a cardiac disorder of different origins. This syndrome is associated to adaptive cardiac and systemic responses, that can fully compensate the underlying cardiac disorder or that can lead to an excessive expansion of the cardiovascular bed with secondary fluid accumulation, cavity effusion and oedema. Among the systemic responses we consider the neuro-hormonal mechanisms (e.g., activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system) and the inflammatory mechanisms. The cardiac responses can be microscopic, at the cardiomyocyte and interstitial level, or macroscopic, as expression of the so called cardiac remodelling. The most important drugs used for the control and treatment of HF are the diuretics, the ACE-inhibitors, and the inotropes. The use of these medications is not aimed to treat specifically the underlying cardiac disease, but rather to control the clinical signs of HF and to increase the patient's quality and quantity of life.
- Publication
Summa, Animali da Compagnia, 2019, Vol 36, Issue 2, p5
- ISSN
1828-5538
- Publication type
Article