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- Title
Role of cancer stem cell ecosystem on breast cancer metastasis and related mouse models.
- Authors
Xilei Peng; Haonan Dong; Lixing Zhang; Suling Liu
- Abstract
This document is a compilation of scientific articles discussing the role of cancer stem cells (CSCs) and the tumor microenvironment (TME) in breast cancer metastasis. It highlights the importance of understanding the mechanisms underlying metastasis to develop effective treatment strategies. The articles cover topics such as the molecular and cellular processes involved in CSC and TME interactions, the correlation between CSCs and vascular mimicry, metabolic reprogramming of CSCs, and the interactions between CSCs and immune cells in the TME. The document also explores the involvement of different cellular components in breast cancer progression and metastasis, and discusses various therapeutic strategies targeting CSCs and the TME. Additionally, it provides insights into the use of mouse models for breast cancer research and the limitations of these models. Overall, this document provides a comprehensive overview of current research in the field and can be a valuable resource for library patrons conducting research on breast cancer.
- Subjects
METASTATIC breast cancer; CANCER stem cells; BREAST; KILLER cell receptors; MEDICAL sciences; LABORATORY mice; TRIPLE-negative breast cancer
- Publication
Zoological Research, 2024, Vol 45, Issue 3, p506
- ISSN
2095-8137
- Publication type
Article
- DOI
10.24272/j.issn.2095-8137.2023.411