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- Title
Prednisone vs. placebo in withdrawal therapy following medication overuse headache.
- Authors
Pageler, L.; Katsarava, Z.; Diener, H.C.; Limmroth, V.
- Abstract
This proof-of-concept study evaluated the efficacy of prednisone for the treatment of withdrawal symptoms in patients with medication overuse headache (MOH) in a randomized, placebo-controlled, double-blind design. Twenty patients were randomized and underwent in-patient withdrawal therapy. The total number of hours with severe or moderate headache within the first 72 and 120 h was significantly lower in the prednisone group. The results show that prednisone might be effective in the treatment of medication withdrawal headache.
- Subjects
PREDNISONE; DRUG efficacy; TREATMENT of drug withdrawal symptoms; PLACEBOS; HEADACHE treatment
- Publication
Cephalalgia, 2008, Vol 28, Issue 2, p152
- ISSN
0333-1024
- Publication type
Article
- DOI
10.1111/j.1468-2982.2007.01488.x