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- Title
Catechol-derived Inhibitors against Quorum Sensing from Retiboletus kauffmanii.
- Authors
Liman ZHOU; Lin WANG; Fandong KONG; Qingyun MA; Qingyi XEE; Haofu DAI; Youxing ZHAO
- Abstract
[Objectives] This study aimed to screen anti-quorum sensing (QS) activity from the constituent of Retiboletus kauffmanii fruit body. [Methods] Chromatographic technology was used to isolate compounds, while well diffusion assay was applied to screen anti-quorum sensing activity. [Results] 12 phenolic compounds were purified from extracts, three catechol-derived compounds at sub-inhibitory concentrations were found to inhibit the production of violacein in Chromobacterium violaceum for the first time. [Conclusions] Three catechol analogs isolated from R. kauffmanii fruit body extract were indicated as quorum sensing inhibitors against C. violaceum.
- Subjects
QUORUM sensing; CHROMOBACTERIUM violaceum; PHENOLS; FRUIT extracts
- Publication
Medicinal Plant, 2021, Vol 12, Issue 1, p68
- ISSN
2152-3924
- Publication type
Article
- DOI
10.19600/j.cnki.issn2152-3924.2021.01.019