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- Title
Hyperventilation and amplified blood pressure response: is there a link?
- Authors
Naschitz, JE; Mussafia-Priselac, R; Peck, ER; Peck, S; Naftali, N; Storch, S; Slobodin, G; Elias, N; Rosner, I
- Abstract
Based on prior studies, the hypothesis that hyperventilation (HV) may have a pressor effect and play a causal role in hypertension has been suggested. The objective of this study was to correlate HV with blood pressure (BP)-change during a postural challenge. Consecutive subjects referred for evaluation of syncope, dizziness, chronic fatigue syndrome (CFS), fibromyalgia, or non-CFS fatigue were assessed with a 10-min supine 30-min head-up tilt test combined with capnography. We selected for analysis the records of patients aged 17-70 years, not taking vasoactive medications, having sitting systolic BP (SBP)<140?mmHg, sitting diastolic BP (DBP)<90?mmHg, and who completed 30?min of tilt. HV was diagnosed when end-tidal pressure of CO2<30?mmHg was recorded consecutively for?10?min. Postural hypertension (PHT) was diagnosed when DBP on tilt?90?mmHg was recorded consecutively for?10?min. DBP-change was computed as (median DBP on tilt)-(median DBP supine). PHT and DBP-change were correlated with HV. A total of 320 patient charts were reviewed. PHT was present in 30 cases. The mean DBP-change in patients with PHT was+9.9?mmHg (s.d. 5.8), with three patients manifesting HV. Of the remaining 290 patients, 56 had HV, their mean DBP-change was -0.3?mmHg (s.d. 7.2). The other 234 patients without HV had a mean DBP-change+0.95?mmHg (s.d. 5.7), comparable to the DBP-change in patients with HV. In, conclusion, posturally induced HV was not associated with an increase in BP, nor was PHT associated with HV, except in a small minority of cases.Journal of Human Hypertension (2005) 19, 381-387. doi:10.1038/sj.jhh.1001830
- Subjects
BLOOD pressure; HYPERTENSION; BLOOD circulation disorders; CARDIOVASCULAR diseases; HYPERVENTILATION; CAPNOGRAPHY; CARBON dioxide in the body
- Publication
Journal of Human Hypertension, 2005, Vol 19, Issue 5, p381
- ISSN
0950-9240
- Publication type
Article
- DOI
10.1038/sj.jhh.1001830