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- Title
Tumori mozga kod dece - dijagnostika i terapija.
- Authors
Nikitović, M. R.; Golubičić, I. V.; Borojević, N. D.; Pekmezović, T. D.; Grujičić, D. M.; Plešinac-Karapandžić, V. S.
- Abstract
During the period 1995-2004 we treated 212 patients (pts) with brain tumors. There were 133 boys and 79 girls, aged from 2,5 yrs up to 18 yrs (Me=9,7 yrs). The majority of pts were in age group (4-16) yrs-179 pts. Supratentorial tumors were diagnosed in 118 pts vs. infratentorial 94 pts. Therapy involved surgery, postoperative radiotherapy with or without chemotherapy. Survival rates were calculated using Caplan-Meier method and differences between curves with log-rank test. During the follow-up period from 1 to 9 year (Me=3 yrs) 5-year disease free survival rate was 55,7%. 79 pts failed to therapy. There was no statistically significant difference in survival according to sex (p=0,123) and age (p=0,367). Pts with supratentorial tumors had statistically significant better survival (p=0,036). Pts with histologic type lowgrade astrocitomas had statistically significant better survival than malignant gliomas, ependymomas and PNET (p=0,0001). Surgery, postoperative radiotherapy and chemotherapy in selected cases are efficient therapeutic approach for pediatric brain tumors.
- Subjects
BRAIN tumors; DIAGNOSIS of tumors in children; TUMOR treatment; PEDIATRIC therapy; RADIOTHERAPY; MEDICAL radiology
- Publication
Acta Chirurgica Iugoslavica, 2009, Vol 56, Issue 4, p19
- ISSN
0354-950X
- Publication type
Article
- DOI
10.2298/ACI0904019N