We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Capecitabine-Based Combination Therapy for Breast Cancer: Implications for Nurses.
- Authors
Frye, Debra K.
- Abstract
Purpose/Objectives: To review available data and implications for nurses of combination regimens containing capecitabine for metastatic breast cancer.Data Sources: Peer-reviewed publications or abstracts from major oncology conferences and reviews of capecitabine focusing on nursing implications.Data Synthesis: Capecitabine has proven efficacy in combination with docetaxel and is under evaluation in the neoadjuvant, adjuvant, and metastatic settings in combination with several oral and IV chemotherapeutic and biologic agents.Conclusions: Capecitabine-containing regimens demonstrate high activity in a range of settings but typically have more complex safety profiles, dose-modification schemes, and scheduling requirements than monotherapy.Implications for Nursing: Patients need to be aware of a wider range of likely side effects and should understand that they have been prescribed combination therapy rather than more simple, single-agent treatments because of its potential to improve outcome.
- Subjects
ONCOLOGY nursing; CANCER treatment; CANCER patients; IMMUNOLOGICAL adjuvants; ANTINEOPLASTIC agents; DISEASES in women
- Publication
Oncology Nursing Forum, 2009, Vol 36, Issue 1, p105
- ISSN
0190-535X
- Publication type
Article
- DOI
10.1188/09.ONF.105-113