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- Title
Pregnancy and perinatal outcome in women with hyperthyroidism
- Authors
Pillar, Nir; Levy, Amalia; Holcberg, Gershon; Sheiner, Eyal
- Abstract
<bold>Objective: </bold>To investigate pregnancy outcome for patients with treated hyperthyroidism.<bold>Methods: </bold>A population-based study was performed comparing all singleton pregnancies of women with and women without hyperthyroidism at the Soroka University Medical Center, Be'er-Sheva, Israel, between January 1988 and January 2007. Stratified analysis, using a multiple logistic regression model, was performed to control for confounders.<bold>Results: </bold>During the study period, there were 185636 singleton deliveries in the medical center. Of these, 189 (0.1%) were from women with hyperthyroidism. Using multivariate analysis with backward elimination, the following risk factors were significantly associated with hyperthyroidism: placental abruption; cesarean delivery; and advanced maternal age. No significant differences regarding perinatal outcome were noted between the groups. Women with hyperthyroidism had significantly higher rates of cesarean delivery than did women without hyperthyroidism (20.1% vs 13.1%; P<0.004), even after controlling for confounders.<bold>Conclusions: </bold>Treated hyperthyroidism was not associated with adverse perinatal outcome. However, hyperthyroidism was found to be an independent risk factor for cesarean delivery.
- Subjects
ISRAEL; HEALTH outcome assessment; HYPERTHYROIDISM; THYROID diseases; PREGNANT women; REGRESSION analysis; DELIVERY (Obstetrics); PATIENTS; THERAPEUTICS; HYPERTHYROIDISM treatment; TREATMENT of pregnancy complications; ACADEMIC medical centers; AGE distribution; CESAREAN section; EVALUATION of medical care; MULTIVARIATE analysis; PREGNANCY; PREGNANCY complications; LOGISTIC regression analysis; RETROSPECTIVE studies; ABRUPTIO placentae; DISEASE complications
- Publication
International Journal of Gynecology & Obstetrics, 2010, Vol 108, Issue 1, p61
- ISSN
0020-7292
- Publication type
journal article
- DOI
10.1016/j.ijgo.2009.08.006