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- Title
Peak Expiratory Flow as an Index of Frailty Syndrome in Older Adults: A Cross-Sectional Study.
- Authors
Magave, J. A.; Bezerra, S. J. S.; Matos, A. P.; Pinto, A. C. P. N.; Pegorari, Maycon Sousa; Ohara, D. G.
- Abstract
Objectives: To compare the obtained and predicted peak expiratory flow (PEF) values between frail, pre-frail, and non-frail older adults; verify the association between PEF and FS; and establish cut-off points for PEF as determinants of frailty syndrome (FS). Design: Cross-sectional study. Location: Macapá, Amapá, Brazil. Participants: Community-based study community-dwelling older people. Methods: PEF was evaluated using a peak-flow meter and FS was evaluated using Fried's frailty phenotype. The statistical analyses performed included a multinomial logistic regression model and Receiver Operating Characteristic (ROC) curves to establish cut-off points for discriminating FS. Results: 409 older adults with a mean age of 70.09±7.22 years were evaluated; of these, 58.7% were pre-frail, and 12.7% were frail. PEF was lower in frail than in pre-frail participants, and lower in pre-frail than in non-frail. Frail and pre-frail older adults obtained lower PEF values than predicted. PEF (% Predicted) was inversely associated with frailty and pre-frailty even after adjustment. Cut-off points were established to discriminate the presence of frailty in older men (PEF≤350L/min; AUC=0.669; sensitivity=76.92%; specificity=52%) and women (PEF≤220L/min; AUC=0.597; sensitivity=71.79%; specificity=46.98%). Conclusions: Frail and pre-frail older adults presented significantly lower PEF than non-frail participants, and these values were lower than predicted. PEF was inversely associated with frailty and pre-frailty. PEF cut-off points can be used as a complementary method to indicate frailty in community-dwelling older adults.
- Subjects
BRAZIL; FRAIL elderly; RESPIRATORY measurements; PULMONARY function tests; MULTIPLE regression analysis; INDEPENDENT living; CROSS-sectional method; RECEIVER operating characteristic curves; EARLY diagnosis; DESCRIPTIVE statistics; OLD age
- Publication
Journal of Nutrition, Health & Aging, 2020, Vol 24, Issue 9, p993
- ISSN
1279-7707
- Publication type
Article
- DOI
10.1007/s12603-020-1509-y