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- Title
Marked Disturbance of Calcium Homeostasis in Mice With Targeted Disruption of the Trpv6 Calcium Channel Gene.
- Authors
Bianco, Suzy D. C.; Ji-Bin Peng; Takanaga, Hitomi; Suzuki, Yoshiro; Crescenzi, Alessandra; Kos, Claudine H.; Liyan Zhuang; Freeman, Michael R.; Gouveia, Cecilia H. A.; Jiangping Wu; Hongyu Luo; Mauro, Theodora; Brown, Edward M.; Hediger, Matthias A.
- Abstract
The article presents a study regarding the marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. Trpv6 mice exhibit an array of abnormalities in multiple tissues. The study indicate that Trpv6 channel plays an important role in calcium homeostasis and in other tissues not directly involved in the process.
- Subjects
CALCIUM channels; ION channels; CALCIUM; HOMEOSTASIS; TISSUES
- Publication
Journal of Bone & Mineral Research, 2007, Vol 22, Issue 2, p274
- ISSN
0884-0431
- Publication type
Article
- DOI
10.1359/JBMR.061110