Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleIle50Val variant of IL4Rα upregulates IgE synthesis and associates with atopic asthma.AuthorsMitsuyasu, Hiromichi; Izuhara, Kenji; Mao, Xiao-Quan; Gao, Pei-Song; Arinobu, Yojiro; Enomoto, Tadao; Kawai, Mitsuru; Sasaki, Sei; Dake, Yasuhiro; Hamasaki, Naotaka; Shirakawa, Taro; Hopkin, Julian M.AbstractReports that the Ile50Val variant of interleukin-4Ralpha upregulates the synthesis of immunoglobulin E. Association with atopic asthma; Analysis of pertinent topics and relevant issues; Implications on genetics.SubjectsIMMUNOGLOBULIN E; INTERLEUKINS; GENETICS of asthmaPublicationNature Genetics, 1998, Vol 19, Issue 2, p119ISSN1061-4036Publication typeArticleDOI10.1038/472