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- Title
Racial Disparity in A1C Independent of Mean Blood Glucose in Children With Type 1 Diabetes.
- Authors
Kamps, Jodi L.; Hempe, James M.; Chalew, Stuart A.
- Abstract
OBJECTIVE- Mean blood glucose (MBG) and MBG-independent factors both influence A 1C levels. Race was related to A1C independent of MBG in adults. The goal of this study was to determine if racial :disparity exists in A1C independent of MBG in children with diabetes. RESEARCH DESIGN AND METHODS -- Participants included 276 children with type 1 diabetes. A1C and MBG were obtained from multiple clinic visits, and a hemoglobin glycation index (HGI) (an assessment of A1C levels independent of MBG) was calculated. A1C and HGI were analyzed controlling for age, diabetes duration, and MBG. RESULTS -- African Americans had statistically significantly higher A1C (9.1 ± 0.1) and HGI (0.64 ± 0.11) than Caucasians (A1C 8.3 ± 0.1, HGI -0.15 ± 0.07) independent of covariates. CONCLUSIONS-- Because of racial disparity in A1C, which is independent of MBG, we recommend that A1C and MBG be used together to make therapeutic decisions for children with diabetes.
- Subjects
BLOOD sugar; DIABETES complications in children; HEMOGLOBINS; THERAPEUTICS; PEOPLE with diabetes
- Publication
Diabetes Care, 2010, Vol 33, Issue 5, p1025
- ISSN
0149-5992
- Publication type
Article
- DOI
10.2337/dc09-1440