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- Title
Nanotechnology Applications in Neuroscience: Advances, Opportunities and Challenges.
- Authors
Cetin, Mesut; Gumru, Salih; Aricioglu, Feyza
- Abstract
Nanotechnology applications in neuroscience: Advances, opportunities and challenges New treatment and prophylaxis needs, which have emerged as the incidence of central nervous system disorders (CNSDs) has increased, have brought two concepts together: neuroscience and nanotechology. Because of the restricton of the blood-brain barrier (BBB), conventional drug delivery systems do not always work to provide the levels of drug molecules to the CNS that are needed for the recovery from CNSDs. Nanotechnology products may provide increased compliance, enhanced bioavailability, better BBB penetration of drug molecules, and a minimized side effect profile. This review considers some important application examples of nanotechnology and micro-electromechanical systems in neuroscience, and drug delivery approaches across the BBB. The major controversies concerning invasive procedures for application of some products and the use of microchips and nanodevices are also discussed.
- Subjects
NANOTECHNOLOGY; NEUROSCIENCES; CENTRAL nervous system diseases; BLOOD-brain barrier; MICROELECTROMECHANICAL systems; DRUG delivery systems; BIOAVAILABILITY
- Publication
Klinik Psikofarmakoloji Bulteni, 2012, Vol 22, Issue 2, p115
- ISSN
1017-7833
- Publication type
Article
- DOI
10.5455/bcp.20120621044747