We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pregnancy complications associated with childhood anxiety disorders.
- Authors
Hirshfeld-Becker, Dina R.; Biederman, Joseph; Faraone, Stephen V.; Robin, Joanna A.; Friedman, Deborah; Rosenthal, Jessica M.; Rosenbaum, Jerrold F.
- Abstract
To determine whether perinatal complications predict childhood anxiety disorders independently of parental psychopathology, we systematically assessed pregnancy and delivery complications and psychopathology in a sample of children (mean age=6.8 years) at high risk for anxiety disorders whose parents had panic disorder with (n=138) or without (n=26) major depression, and in contrast groups of offspring of parents with major depression alone (n=47), or no mood or anxiety disorders (n=95; total N=306). Psychopathology in the children was assessed by structured diagnostic interviews (K-SADS), and pregnancy and delivery complications were assessed using the developmental history module of the DICA-P. Number of pregnancy complications predicted multiple childhood anxiety disorders independently of parental diagnosis (odds ratio=1.6 [1.4–2.0]). This effect was accounted for by heavy bleeding requiring bed-rest, hypertension, illness requiring medical attention, and serious family problems. Associations remained significant when lifetime child mood and disruptive behavior disorders were covaried. Results suggest that prenatal stressors may increase a child's risk for anxiety disorders beyond the risk conferred by parental psychopathology alone. Depression and Anxiety 19:152–162, 2004. © 2004 Wiley-Liss, Inc.
- Subjects
PREGNANCY; ANXIETY; CHILDREN; PATHOLOGICAL psychology; CHILD psychiatry
- Publication
Depression & Anxiety (1091-4269), 2004, Vol 19, Issue 3, p152
- ISSN
1091-4269
- Publication type
Article
- DOI
10.1002/da.20007