We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Amination of Aryl Halides and Esters Using Intensified Continuous Flow Processing.
- Authors
Kohl, Thomas M.; Hornung, Christian H.; Tsanaktsidis, John
- Abstract
Significant process intensification of the amination reactions of aryl halides and esters has been demonstrated using continuous flow processing. Using this technology traditionally difficult amination reactions have been performed safely at elevated temperatures. These reactions were successfully conducted on laboratory scale coil reactor modules with 1 mm internal diameter (ID) and on a preparatory scale tubular reactor with 6 mm ID containing static mixers.
- Subjects
AMINATION kinetics; ARYL halides; ESTERS; VOIGT reaction; TUBULAR reactors; THERAPEUTICS
- Publication
Molecules, 2015, Vol 20, Issue 10, p17860
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules201017860