Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.Title1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs.AuthorsJai Moo Shin; Sachs, George; Young-moon Cho; Garst, MichaelAbstractNew arylsulfonyl proton pump inhibitor (PPI) prodrug forms were synthesized. These prodrugs provided longer residence time of an effective PPI plasma concentration, resulting in better gastric acid inhibition.SubjectsPROTON pump inhibitors; BENZIMIDAZOLES; ANTIBODY-directed enzyme prodrug therapy; PRODRUGS; ENZYME inhibitors; GASTRIC acid; BIOSYNTHESIS; CHEMICAL bonds; BIOCHEMISTRYPublicationMolecules, 2009, Vol 14, Issue 12, p5247ISSN1420-3049Publication typeArticleDOI10.3390/molecules14125247