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- Title
The Drug Changing Sensitivity and Resistance Pattern of Different Antibiotics and their Minimum Inhibitory Concentration against Salmonella.
- Authors
Wani, Nisar Ahmad; Kannaiyan, Jaianand; Paulraj, Balaji; Veeramani, Veeramanikandan
- Abstract
In the present study, MDRP shows that ampicillin, cotrimoxazole, gentamycin, tetracycline, were resistant. Whereas ceftriaxone with sulbactam, ciprofloxacin, ofloxacin was sensitive. The azithromycin and cefpodoxime were intermediate against S. typhi. The antibiotic susceptibility pattern of S. typhi during the period from Sep 2016 to June 2017and it was found that out of 676 the most sensitive antibiotics were ceftriaxone and sulbactam 90 (100%), ciprofloxacin 90 (100%) and ofloxacin 90 (100%) whereas the most resistant antibiotics were tetracycline 237 (87.77%) and amoxycillin 225 (83.33%). The change in sensitivity pattern during the period of Sep 2016 to June 2017, July 2016 to 1 April 2018 and May 2018 to Feb 2019 of the drug ceftriaxone and sulbactam, is 100%. The drug cefuroxime is 97.77%, 100 %, and 96.60%. The drug ciprofloxacin 100%, 100%, and 97.57%. The drug ofloxacin is 100%, 94.00%, and 92.23%. The drug amikacin 96.66%, 80.00%, and 50.48%. Out of 676 isolates of S. typhi, the MDR for two drug combination cotrimoxazole and nalidixic acid is 35 (5.17%).
- Subjects
ANTIBIOTICS; CEFTRIAXONE; CEFUROXIME; SALMONELLA; AMIKACIN; TETRACYCLINES
- Publication
Journal of Drug Delivery & Therapeutics, 2019, Vol 9, Issue 3, p171
- ISSN
2250-1177
- Publication type
Article
- DOI
10.22270/jddt.v9i3.2638